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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fca1104d53a03e9d974d64600bb312b7895f851e0199a09d2aa737cf9fc7c17' 
  AND token = '21zeXQEwrvvPpVURQr1nyBIEa5uC9XtHVG813Wxntjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}