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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '482bc2782ad13323061611b1063f6aeba9e64ff5465fc3f53189f74706733ecc' 
  AND token = '01zNMvRIQCcBIGg486u4ind0ZwuEQspFpW8irikPYS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}