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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6053274069ba41b1d122ff82915244399a83c6fe2111b8f8d7bc3c2ad99a90e' 
  AND token = 'VsYS/IJ4I0mgI9+NSGTKUkuunNon2jNto+MD1jZns/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}