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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e19dd585a504cfc40fe4db40e6dcadae2a9794fa489f592f6721b21f27d9bcc1' 
  AND token = 'J+nWL93uU6lNF0SGqHaB/DTCXL9ZaK73EJZArbIJe5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}