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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec4251b3a7b1ac9f6a8dce9d3bb01085d96f97147363d21a693b7e50169f42ea' 
  AND token = '96Gm2Y16p/OPyPy3PHnHtlP+trUpC5qLJASYiHjxTZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}