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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '005a4b888bb777f47c0e1de35441e9215146020f90a3caadef057b0e8a04bf89' 
  AND token = '1k2lKKCYHAbZTZ5jmk55fx6aYx+vaTTPHduyPSRkn5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}