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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b176df92573f2ac15c2ccbb3028839dc4d40d4ca7fb14b069afb294c116db18' 
  AND token = 'EeAeU1JVY/WbVIj6Diz/+BSNdRAuOSIM3dkdOJLYvq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}