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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6795d66a0f25cc92ee4ffa494d34423ff457cc9ad2798f65689f7438495caf3b' 
  AND token = 'Cw3Ef0aEApVygXwzC4WeOGRSkHJXIEeFI/GEHEjx0Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}