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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a47e6bfed9c51a54907751f24afd46e28c16424cc90a202dc5f6e47e6792f74' 
  AND token = 'Yhj61JO9EYCv12EEZvAKmo2JYcSUpBu2sLb6rWGdH9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}