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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5a4eb604b9a8deb02ae9729a4b40a997f9453594053ebdd18eac7c73b9077b5' 
  AND token = 'wKS+/701nNfXtpD7vARCSc7CwsHrMOP6C+bkI1c1/Po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}