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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7380f83c4cb9aa1934e8f427a2f0bf67941aec82f0d358d10633c747f3d88a6' 
  AND token = 'Edh35u+RbmHQNJiyLaggBmppu293lbWX2630UmYwQ38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}