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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9df975bef15f7f2f65970d783016733984d8bcc375800c4fde53850ee935b3b4' 
  AND token = 'qEgFcfOuseLtrm2wEiNmd6n/xqoplEc4QU4kNoTL1s0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}