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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800f3e11bd3a92c77fbb1707219e6879d3f1dc88ed6b38e5eb445e0438a1adc8' 
  AND token = 'Efw6PNNTlXVBmCFONWVLL1x3ivegECDDBFpsTy6U9JU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}