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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42a395e2d55b4bac8e3207b50598008ee7bf4834c69fe2c7e6603999a71ed030' 
  AND token = 'oOcW11mac7619aUApr9LFVhRTx5TkpvdHgoblqX1nXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}