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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f433dc130088e5c0695f9c6b26f7d4035366eda4b650ac35b3b6dc8be387e37' 
  AND token = 'p4/RyjR21Os0S+rxVU1P6zkAFBaQ7z9XzpEb+V626F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}