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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78aa58a8d0d094a95a089b3e4bd891837c20d755b0f77612daf37cd08214828c' 
  AND token = 'secs1Ea0802k+bkfJowHLGi81a8MC2gZDYHqBpai52E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}