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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b37e911d4e1cbd7234ef25b646533985fd1315dd02637033ce72a6d2474274f' 
  AND token = 'ng1Fk0gOZQGXJZhTbXLQAFU0Hxf+/1UcO9oubsjEz64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}