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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9313fd6481e4d548bf94f5798082ece1ec95a475691184fdb0dbb930f259f2ed' 
  AND token = 'VL64O2YbXONuHhmO5gw2aEGs2KnAPjK/jmb4uAS4ldc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}