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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '224b989adeb3fe0c55aa530526989504b94b27b7f622cc9bb511054e182e8576' 
  AND token = 'ORwf2ksUsWNISM/Hpf5Dxg+LxA+e1mM+Xk9lxcuSvcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}