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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f2c026a917090138219410925351b711f329be2b48fe90d1f4d9166336713db' 
  AND token = '8tcvFTpUe5hSAQaysaxEFv0VgamHp6V1dor2rdl7Tjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}