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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87da1c242e5ff56acaadb84311f0946a2c451a71c81c0b2a2cbec51880b7a049' 
  AND token = 'Nec9a/HtBr7UOmEmG58rR/G0FRgchlGlpI8N8oeaDMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}