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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5498327fda5bbd7ada0b270f0d543d02b73683e34a29d7fbf7894195f81c187' 
  AND token = '10uHOuQgcOC642MFrdOq8SRcBYMA04NG7EmR6jD01tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}