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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bee527214cb92d34e0c3344db3e9310149af4c8863b0733fd435d61f8a131fd' 
  AND token = '2Nr9Ri75mke97t0YDjlgkBwsDB+3XT4QCy0HJsjgxsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}