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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac143dd1af33d9be9569c2bd627a27d892905eea2fb8bef2d3fdf1492590d4f2' 
  AND token = 'gb7+C7oCtmO5yS2MMWPF9yhdOSP6XE6JPqgiz6q+dJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}