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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '345fa2b07749f96c641cd3fccd8110ab11b1c28c41152076ce5016ea66570b97' 
  AND token = '12UZmIZiXHaJ5kzbDBSU0IwENORq1H+Z+HpXGRe3qmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}