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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9be22244a481d5d30c5fde09149628d3c75017bf79a1ae065811c5d5387537be' 
  AND token = 'CBO6xLeVI4yIHmoiueWbizk/HcQrMfK3PlTC8LESk9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}