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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '963e697423bce41ff0b2162d6bf3d269e02f989ec2039e6c5ee4b18a4d15ef3f' 
  AND token = 'zVjDF0iQnnxmUxdXVkx71jfoI+QMGVZ28PucBLHrGz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}