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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77c37853721af7bc5c8d09233d6014f1b5265a2c0128eb73a949adf595b43963' 
  AND token = 'ztUxJUmnpxIhtrjWlStlwp5I1pCTMD89M5bWjHyjdBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}