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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b4f34cfe5fb2776e0432467b0b38d684ace0ec566099b5f1d3934df701b88fc' 
  AND token = 'uQbuTtGhjfd7gVoPNbk0k6b2JmwTedUtIQmMC8Yp9U4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}