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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5105ec296d2c85b16f7460ac541587777eb664c8472b1f203bc8fe26d6691491' 
  AND token = 'mQAi5IXptSMS1+JHFsPHdK7M9KN7deGtYfWiWEOpdz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}