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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efccbfd94c9e26aada598a1ef142608f4a0d3af6a8130d5c89e834907994da31' 
  AND token = 'WckdMByeEKJc/AxXJ46AkBUl18UkXnhmnswjlX5uYwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}