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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ec7ac20f3c0fb87ad8a94612fdceb36bcfc76960f6caecabd93e91d7d31e38' 
  AND token = 'Q3pFQUDnHAj+jxR7OS+Wxu7aHoSoHVEvN6TKOIFpxhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}