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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3da593f45cbf239f606f9d8bc5d02c52447ea9f0ebc16598a9873116d255f864' 
  AND token = 't53SEyKD311MWKmAtstJ05mFXgxeQNy3DT4gTQUwGHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}