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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d073f12de1a2b5c35456e93584988d5db15c18c68b26e81a1aa44d69851bb2b' 
  AND token = 'rewVLBQdIvl2C8jgLqdAfDton2twZ7zcrVbA1Yd5OY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}