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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a67e0ec7ee83eca4d5bbb160eb8ab6d10de15e31ba3a0ed1d7fb9f2e534c18b' 
  AND token = '8kNdA8jm1a/bDSMLvrL+3zD2VM5E8vlFNBBL7SBdmoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}