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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65d11dc4c6e0adcfe38e225674a3a313e7e8ebe0df338bbc4adfb7e604147641' 
  AND token = 'fkhOG0gsRElnI0Sr1GzpJLrcyTstfM9Gh2uOgKYFLHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}