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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '761cca685a6bbc96ec0f64f96074806622763f31c686769596c7f2f9f0e7dd4e' 
  AND token = 'zFA99ISO0ITvzY3kJuhCZ+7Uq5qpv+rjB6LYvM7AD0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}