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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71e4af5b0d92b2910e7160366882b43e92492591c268855f5994a7c00463b2f3' 
  AND token = 'QBQpOjze4I5OBzy7YpxuQ3DnsPtwN4j0laxGQd3M0pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}