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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06e53fe456f3261661c68234e5fb2c90ebdce4eab2f7a1ac3f572b1c85cc3d74' 
  AND token = 'z5bA9ldU3qhGdj3kzAs+xonJ7I8A4HgMz64DN9vCuC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}