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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d0f0a28a11542b50d3b085468bd064b0d6c1bcdb78365d158b4dc5ba72ac61a' 
  AND token = 'Uf7TS7bwmVEi5HlsNn6TKngTjHC1aqJ2itvhUtin2p8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}