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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aa89a9cd7c050e41c0d46dd19af44316e57ebc3f4234049c8b5d7284f513c36' 
  AND token = 'RvqtnCyRQhJN/pSOpI8C2DuVWSqEHB09W8/MzRQki6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}