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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4042adce887a018a5f8b758ecdb75bdb7385ded0cef6a8c9707aca8301b19568' 
  AND token = 'yvS4+n+fVaqLBbkU3V1O5UcM5i9V1bEKtoSVWnTTbjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}