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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '189a097f7fd81577f708dcfeee11c9149e5e34e07aa5c8e40e484af4bb4c77d9' 
  AND token = '4yHCJMD1L0AB8MBREpP+8IpnemHXlJYBHR8zwZV9YwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}