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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca5cb5f6cb6a23b85bf40f6517be5e4d9f7bfe62045cc21468e508d2e20cc89c' 
  AND token = 'POGPRYoBniOE6lYqC3dXwDG0CsI4Xd81IRkN8rKtQBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}