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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '850953b822a1c70150bbba8236acdb0c0b97adbd13f39d518503219a08933f93' 
  AND token = 'tJT6HoRDtcnFl0chUmZyt/vt+1EiWZ3oTJlsX4ZwEkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}