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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0052eb4e32df2284a5e64f92cd5e6f12a92228814ba79d5cc34fa4a48d81b14' 
  AND token = '+ToRy4HAyDwFyRofDRByNahL6l789qbxpR7B4nvPS4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}