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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a48bc052183cee335986b4adc7c3aea49d45ca70812de703be57a6a0c14e8dd' 
  AND token = 'XpHeQB60jonzmEWDGQnHHdO9ya9YhyxhdXJeRBwNcZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}