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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a8f63dd7a469f905bff975c189f76c1116b37f41978d4b8af756e693a0c8fd8' 
  AND token = 'SmZVR5TVC630UwtJ0HrnOBK+VD9t60hN5+BRKICIT78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}