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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e821d8f8ca83cf6688e1f95c645961722b4b940a9111820d01ccf3e192da1365' 
  AND token = 'ZDf/lBOe7ZXafZqWKPm7qfAgroFH9ZnOdo9dJ2H1H4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}