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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0441e8e3d0bd4e48f080fb6247d1eea37060dd6036adc76129e890dd59039b29' 
  AND token = 'oVxNXowi84YF4CSwlC7TjhRrslGdS/Z/VHR4mE6uDTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}